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Clomid And Ovulation
Of women whose only fertility problem is irregular or no ovulation at all, about 80 percent will ovulate and about 50 percent will become pregnant within six months of clomiphene treatments. About three percent of women on clomiphene have a multiple pregnancy, usually twins, compared with about one percent in the general population.
A woman who ovulates infrequently, say at six-week intervals or less often, is also a good candidate for clomiphene therapy, since clomiphene will induce ovulation more frequently. The more a woman ovulates, the more opportunities her mature eggs have to be exposed to her husband's sperm and, therefore, the greater her chance to become pregnant.
For a woman who has normal, spontaneous ovulation, driving the pituitary harder with clomiphene won't make ovulation any more normal. If a woman has taken clomiphene for several cycles without becoming pregnant, then she and her fertility specialist should investigate other conditions that may be preventing her pregnancy.
It may take time to establish an appropriate and effective dosage for each person. Once that is established, you should expect to ovulate 5-8 days after the last pill is taken. If you do not conceive in that cycle, AF will usually arrive three weeks after the last pill.
If there is a male factor involved in your inability to get pregnant, Clomid will not fix the problem. In fact, that's why most physicians suggest a thorough exam and adequate laboratory testing before beginning Clomid. One would not want to arbitrarily begin taking Clomid if there are other problems that need to be addressed, as it would not necessarily be of any value in the face of other unrelated factors. Especially if you're paying out of pocket, unproductive overuse of the drug can get expensive.
Ovulation most often occurs from 5 to 10 days after a course of clomiphene citrate tablets USP. Coitus should be timed to coincide with the expected time of ovulation. Appropriate tests to determine ovulation may be useful during this time.
Ovulation should be checked after commencing clomiphene induction of ovulation. One can use measurement of basal body temperature, checking for the rise associated with ovulation. Alternatively, a serum progesterone estimation at day 21 or serial ultrasound scans will confirm this.
Clomid And Luteal Phase Defect
Clomiphene is also often effective for a woman with luteal phase defect (LPD). A woman with LPD may begin the ovulation process properly, but her ovarian function becomes disrupted, resulting in low production of the hormone progesterone in the luteal phase of the menstrual cycle. Following ovulation, the ovary produces progesterone, the hormone needed to prepare the uterine lining for implantation of the fertilized egg, which has divided and entered the uterine cavity. A fall in progesterone levels in the blood during this critical time can interfere with early embryo implantation or, even if a fertilized egg has already implanted, cause a woman to menstruate too early and end a pregnancy within a few days after implantation.
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