|
|
Clomid Clinical Studies
During clinical investigations, 7578 patients received clomiphene citrate tablets USP some of whom had impediments to ovulation other than ovulatory dysfunction (see INDICATIONS AND USAGE). In those clinical trials successful therapy characterized by pregnancy occurred in approximately 30% of these patients.
Of the reported pregnancies, the incidence of multiple pregnancies was 7.98% : 6.9% twin, 0.5% triplet, 0.3% quadruplet, and 0.1 % quintuplet. Of the 165 twin pregnancies for which sufficient information was available, the ratio of monozygotic to dizygotic twins was about 1:5. Table 1 reports the survival rate of the live multiple births. A sextuplet birth was reported after completion of original clinical studies: none of the sextuplets survived (each weighed less than 400 g). although each appeared grossly normal.
|
|
