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Clomid Side Effects
Clomiphene is a very safe medication with relatively few contraindications. Preexisting liver disease is one contraindication since clomiphene is metabolized by the liver. Enlarged ovaries are also a contraindication since clomiphene may occasionally produce hyperstimulation of the ovaries.
Just as women's bodies are so different from one another, their reactions to Clomid vary tremendously. Some women have virtually no side effects. Others do, but they are more frequently related to emotions. As Sara describes her three months on Clomid before moving on to other medications: "Hormone hell is probably the best way to describe it. By the third or fourth day of taking it, I would become hysterical for absolutely no reason. I felt as if I had no control over my body. I began to wonder if this was worth it. But, it only lasted a few days, and we all got through it. But it wasn't fun."
Some side effects may include mood swings, hot flashes, breast tenderness, and thinning of the uterine lining. Multiple gestation pregnancies may occur (about an 8-10 percent occurrence in those who get pregnant). Ironically, Clomid can cause hostile fertile mucous and thins the uterine lining in over 30 percent of the women who use it. The hostile mucus kills sperm, and the thin uterine can prevent implantation or cause an early miscarriage.
As with most ovulation-inducing drugs, there is a risk of ovarian hyperstimulation. Cysts can erupt and ovaries can be enlarged. This is rarely serious and is more common with other fertility medications. However, if you are taking this medication and have unexplained pain, call your doctor. A quick ultrasound can determine if there are any problems. This drug should not be taken if you are pregnant or have a history of liver disease.
Clomiphene citrate has no apparent progestational, androgenic, or antrandrogenic effects and does not appear to interfere with pituitary-adrenal or pituitary-thyroid function. Although there is no evidence of a carryover effect of clomiphene citrate tablets USP, spontaneous ovulatory menses have been noted in some patients after clomiphene citrate tablets USP therapy.
The following adverse events have been reported in fewer than 1% of patients in clinical trails: Acute abdomen, appetite increase, constipation, dermatitis or rash, depression, diarrhea, dizziness, fatigue, hair loss/dry hair, increased urinary frequency/volume, insomnia, light-headedness, nervous tension, vaginal dryness, vertigo, weight gain/loss.
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